Wise Prescribing and Deprescribing: Opioid Skills for the Frontline Clinician References


Abid Azam, M., et al. (2017). Acceptance and commitment therapy to manage pain and opioid use after major surgery: preliminary outcomes from the Toronto General Hospital Transitional Pain Service. Canadian Journal of Pain, 1(1), 37-49.

Alberta Health Services. Naloxone (Narcan) Drug Information. Retrieved from https://www.albertahealthservices.ca/assets/healthinfo/mh/hi-amh-naloxone-drug-information-sheet.pdf

Alberta Health Services. Opioid overdose signs and symptoms poster. Retrieved from https://www.albertahealthservices.ca/assets/info/hp/edu/if-hp-edu-amh-fentanyl-poster.pdf

Alberta Health Services. SAVE ME. Retrieved from https://www.albertahealthservices.ca/assets/healthinfo/mh/hi-amh-save-me.pdf

Alberta Health Services. Stop ODs – Get Naloxone. Retrieved from http://www.albertahealthservices.ca/info/Page15586.aspx ; https://www.albertahealthservices.ca/info/page12491.aspx#getistribution/Dashboard8#!/publish-confirm

Alberta Health Services. Take home Naloxone client handout. Retrieved from http://www.albertahealthservices.ca/assets/healthinfo/mh/hi-amh-thn-presentation-for-clients.pdf

Alberta Health Services. Take home Naloxone kit brochure. Retrieved from https://www.albertahealthservices.ca/assets/healthinfo/mh/hi-amh-thn-kit-brochure.pdf

Alberta Health Services. Take home Naloxone presentation for trainers. Retrieved from https://www.albertahealthservices.ca/assets/healthinfo/mh/hi-amh-thn-presentation-for-trainers.pdf

Al-Hasani, R., & Bruchas, M. R. (2011). Molecular mechanisms of opioid receptor-dependent signaling and behavior. Anesthesiology: The Journal of the American Society of Anesthesiologists, 115(6), 1363-1381.

Allen, J. (2011, December 20). Office-based Treatment of Opioid Dependence. Practical Pain Management, 6(2). Retrieved from https://www.practicalpainmanagement.com/treatments/pharmacological/opioids/office-based-treatment-opioid-dependence

Andreassen, T. N., et al. (2011). Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients. European journal of clinical pharmacology, 67(5), 493-506.

Benarroch, E. E. (2012). Endogenous opioid systems Current concepts and clinical correlations. Neurology, 79(8), 807-814.

Berna, C., Kulich, R. J., & Rathmell, J. P. (2015, June). Tapering long-term opioid therapy in chronic noncancer pain: Evidence and recommendations for everyday practice. In Mayo Clinic Proceedings (Vol. 90, No. 6, pp. 828-842). Elsevier.

Busch, A. M., & Borrelli, B. (2012). Valued life activities and readiness to quit smoking among mobility-impaired smokers. Health Psychology, 31(1), 122.

Busse, J. (2017). The 2017 Canadian guideline for opioids for chronic non-cancer pain. Hamilton, ON. Retrieved from http://nationalpaincentre.mcmaster.ca/guidelines.html

CADTH. (2017, April 5). Strategies for the reduction or discontinuation of opioids: guidelines.  Retrieved from https://cadth.ca/sites/default/files/pdf/htis/2017/RB1078%20-%20Opioid%20Tapering%20Final.pdf

Calgary Laboratory Services. (2017, May 5). Drugs of Abuse Testing Attach1 Triage Screen Characteristics. Retrieved from http://www.calgarylabservices.com/files/LabTests/AlphabeticalListing/DAU.pdf

Canada: National Opioid Use Guideline Group (NOUGG). (2010). Canadian Guideline for Safe and Effective Use of Opioids for Chronic Non-Cancer Pain. Retrieved from http://nationalpaincentre.mcmaster.ca/opioid/

Canadian Agency for Drugs and Technologies in Health (CADTH). (March 2017). Opioid formulations with tamper-resistance or abuse-deterrent features — products and policies. Retrieved from https://cadth.ca/dv/tamper-resistant-formulations-of-opioids

Carullo, V., Fitz-James, I., & Delphin, E. (2015). Opioid-induced hyperalgesia: a diagnostic dilemma. Journal of pain & palliative care pharmacotherapy, 29(4), 378-384.

Centers for Disease Control and Prevention (CDC). Calculating total daily dose of opioids for safer dosage. Retrieved from https://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf

Centers for Disease Control and Prevention (CDC). CDC guideline for prescribing opioids for chronic pain. Retrieved from https://www.cdc.gov/drugoverdose/pdf/guidelines_at-a-glance-a.pdf

Centers for Disease Control and Prevention (CDC). (August 2017). Factsheet CDC Guideline for Prescribing Opioids for Chronic Pain. Retrieved from https://www.cdc.gov/drugoverdose/pdf/guidelines_at-a-glance-a.pdf

Centers for Disease Control and Prevention (CDC). Pocket Guide: Tapering opioids for chronic pain. Retrieved from  https://www.cdc.gov/drugoverdose/pdf/clinical_pocket_guide_tapering-a.pdf

Centre for Addiction and Mental Health (CAMH). Opioid misuse and addiction toolkit. Retrieved from https://www.porticonetwork.ca/web/opioid-toolkit/assessment/urine-drug-testing

Centre for Addiction and Mental Health (CAMH). (April 2012). Opioid advice: switching opioids safely to prevent overdose for outpatients prescribed opioids for chronic pain. Retrieved from https://www.porticonetwork.ca/web/knowledgex-archive/primary-care/prescription-opioid-advice/switching-opioids-prevent-overdose-opioids-chronic-pain

Centre for Addiction and Mental Health (CAMH). (Oct 2016). Prescription Opioid Policy Framework. Retrieved from https://www.csam-smca.org/wp-content/uploads/2016/12/CAMH-Policy-Framework.pdf

Centre for Addiction and Mental Health (CAMH). Primary care addiction toolkit. Retrieved from https://www.porticonetwork.ca/web/fundamentals-addiction-toolkit/introduction/defining-addiction

Chaverneff, F. (May 18, 2017). Chronic pain treatment outcomes influenced by nonspecific factors. Clinical Pain Advisor. Retrieved from   https://www.clinicalpainadvisor.com/aps-2017/contextual-factors-influence-the-outcomes-of-treatments-for-chronic-pain/article/662851/

Cherkin, D. C., et al. (2016). Effect of mindfulness-based stress reduction vs cognitive behavioral therapy or usual care on back pain and functional limitations in adults with chronic low back pain: a randomized clinical trial. Jama, 315(12), 1240-1249.

Chou, R., et al. (2009). Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. The Journal of Pain, 10(2), 113-130.

Chu, L. F., Clark, D. J., & Angst, M. S. (2006). Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study. The Journal of Pain, 7(1), 43-48.

Clinical Tools. (2018). Opioid Classification: Agonists, Partial Agonists, and Antagonists. Retrieved from http://www.buppractice.com/node/4816

College of Pharmacists of British Columbia. (2016, April 5). Community Pharmacy Distribution of Naloxone. [PowerPoint slides]. Retrieved from https://www.slideshare.net/bcpharmacists/naloxone-training-presentation-70758933

Corbett, A. D., Henderson, G., McKnight, A. T., & Paterson, S. J. (2006). 75 years of opioid research: the exciting but vain quest for the Holy Grail. British journal of pharmacology, 147(S1).

Dowell, D., Haegerich, T. M., & Chou, R. (2016). CDC guideline for prescribing opioids for chronic pain—United States, 2016. Jama, 315(15), 1624-1645.

Fine, P. G., & Portenoy, R. K. (2009). Establishing “best practices” for opioid rotation: conclusions of an expert panel. Journal of pain and symptom management, 38(3), 418-425.

Firouzian A, et al. (2018). Ultra-low-dose naloxone as an adjuvant to patient controlled analgesia (PCA) with morphine for postoperative pain relief following lumbar discectomy: a double-blind, randomized, placebo-controlled trial. J Neurosurg Anesthesiol, 30(1):26-31.

Frank, J. W., et al. (2017). Patient outcomes in dose reduction or discontinuation of long-term opioid therapy: a systematic review. Annals of internal medicine, 167(3), 181-191.

Fudin J and Wegrzyn EL. (2017). Opioid medications: dosages, adverse events, and patient education.  American Pharmacists Association Pain Institute.

Garland, E. L., et al. (2017). Randomized Controlled Trial of Brief Mindfulness Training and Hypnotic Suggestion for Acute Pain Relief in the Hospital Setting. Journal of general internal medicine, 32(10), 1106-1113.

Gomes, T., et al. (2011). Trends in opioid use and dosing among socio-economically disadvantaged patients. Open Medicine, 5(1), e13.

Government of Canada. (2015, January 5). Frequently Asked Questions – Narcotic Control Regulations. Retrieved from https://www.canada.ca/en/health-canada/corporate/about-health-canada/legislation-guidelines/acts-regulations/frequently-asked-questions-narcotic-control-regulations.html

Grens, K. (2014, February 1). Pain and Progress: Is it possible to make a nonaddictive opioid painkiller? The Scientist. Adapted from https://www.the-scientist.com/?articles.view/articleNo/38989/title/Pain-and-Progress/

Harvard Medical School. (July 2011). How addiction hijacks the brain. Retrieved from https://www.health.harvard.edu/newsletter_article/how-addiction-hijacks-the-brain

Hoffmann, T. C., & Del Mar, C. (2015). Patients’ expectations of the benefits and harms of treatments, screening, and tests: a systematic review. JAMA internal medicine, 175(2), 274-286.

Lembke, A., Humphreys, K., & Newmark, J. (2016). Weighing the Risks and Benefits of Chronic Opioid Therapy. American family physician, 93(12).

Lichtenstein, E., & Hollis, J. (1992). Patient referral to a smoking cessation program: who follows through?. The Journal of family practice.

Marion Lee, M., Sanford Silverman, M., Hans Hansen, M., & Vikram Patel, M. D. (2011). A comprehensive review of opioid-induced hyperalgesia. Pain physician, 14, 145-161.

Martin, C., et al. (2016). Controlled-release of opioids for improved pain management. Materials Today, 19(9), 491-502.

Miller, WR & Rollnick S (2002). Motivational Interviewing:  Preparing people for change (2nd Ed). Guildford Press: NY.

Moseley, G. L., & Butler, D. S. (2017). Explain pain supercharged. Adelaide: Noigroup Publications.

Moseley, G. L. (2017). Innovative treatments for back pain. Pain, 158, S2-S10.

Moseley, G. L. (2016, March 4). Pain: Do You Really Get It? [Video file]. Retrieved from https://www.youtube.com/watch?v=gBlkhFRV53w

National Institute on Drug Abuse. (March 2018). What are the immediate (short-term) effects of heroin use? Retrieved from https://www.drugabuse.gov/publications/research-reports/heroin/what-are-immediate-short-term-effects-heroin-use

Nordgren, L. F., van der Pligt, J., & van Harreveld, F. (2008). The instability of health cognitions: Visceral states influence self-efficacy and related health beliefs. Health Psychology, 27(6), 722.

Pathan, H., & Williams, J. (2012). Basic opioid pharmacology: an update. British journal of pain, 6(1), 11-16.

Patten DK et al. (2018). The safety and efficacy of low-dose naltrexone in the management of chronic pain and inflammation in multiple sclerosis, fibromyalgia, Crohn’s disease, and other chronic pain disorders. Pharmacotherapy, 38(3):382-389.

Pedersen, L., Borchgrevink, P. C., Riphagen, I. I., & Fredheim, O. M. S. (2014). Long‐or short‐acting opioids for chronic non‐malignant pain? A qualitative systematic review. Acta Anaesthesiologica Scandinavica, 58(4), 390-401.

Pesce, A., West, C., Egan City, K., & Strickland, J. (2012). Interpretation of urine drug testing in pain patients. Pain Medicine, 13(7), 868-885.

Perz, C. A., DiClemente, C. C., & Carbonari, J. P. (1996). Doing the right thing at the right time? The interaction of stages and processes of change in successful smoking cessation. Health Psychology, 15(6), 462.

Prochaska et al. (1994). Changing for good. NY: HarperCollins, p,167

Quigley, C. (2004). Opioid switching to improve pain relief and drug tolerability. Cochrane Database Syst Rev, 3(3).

Regnard, C., & Pelham, A. (2003). Severe respiratory depression and sedation with transdermal fentanyl: four case studies. Palliative medicine, 17(8), 714-716.

Ries, R. K., Miller, S. C., & Fiellin, D. A. (Eds.). (2009). Principles of addiction medicine. Lippincott Williams & Wilkins.

Roeckel, L. A., Le Coz, G. M., Gavériaux-Ruff, C., & Simonin, F. (2016). Opioid-induced hyperalgesia: cellular and molecular mechanisms. Neuroscience, 338, 160-182.

Schuckit, M. A. (2016). Treatment of opioid-use disorders. New England Journal of Medicine, 375(4), 357-368.

Schumacher MA, Basbaum AI, Naidu RK. Opioid Agonists & Antagonists. In: Katzung BG, editor. Basic & Clinical Pharmacology, 14 e, 2017 [online]. New York, NY: McGraw-Hill. Retrieved from http://accessmedicine.mhmedical.com

Smith, H. S., & Peppin, J. F. (2014). Toward a systematic approach to opioid rotation. Journal of pain research, 7, 589.

Staal, J. B., de Bie, R. A., de Vet, H. C., Hildebrandt, J., & Nelemans, P. (2009). Injection therapy for subacute and chronic low back pain: an updated Cochrane review. Spine, 34(1), 49-59.

Strang, J. (2015). Death matters: understanding heroin/opiate overdose risk and testing potential to prevent deaths. Addiction, 110(S2), 27-35.

Sullivan, M.D., et al. (2016). Prescription opioid taper support for outpatients with chronic pain: A randomized controlled trial. The Journal of Pain, 18(3) 308-318.

Thielke, S. M., et al. (2014). Do patient-perceived pros and cons of opioids predict sustained higher-dose use?. The Clinical journal of pain, 30(2).

Thielke, S. M., et al. (2017). A prospective study of predictors of long-term opioid use among patients with chronic noncancer pain. The Clinical journal of pain, 33(3), 198-204.

Turner, J. A., et al. (2014). Chronic opioid therapy urine drug testing in primary care: prevalence and predictors of aberrant results. Journal of general internal medicine, 29(12), 1663-1671.

Velasquez MM, Maurer GG, Crouch C & DiClemente CC. (2001). Group Treatment for Substance Abuse.  Guilford Press:  NY, p.46

Vissers, K. C. P., et al. (2010). Opioid rotation in the management of chronic pain: where is the evidence?. Pain practice, 10(2), 85-93.

Wall, P. D., & McMahon, S. B. (1986). The relationship of perceived pain to afferent nerve impulses. Trends in Neurosciences, 9, 254-255.

Webster, L. R., & Fine, P. G. (2012). Review and critique of opioid rotation practices and associated risks of toxicity. Pain Medicine, 13(4), 562-570.

Webster, L. R., & Fine, P. G. (2012). Overdose deaths demand a new paradigm for opioid rotation. Pain medicine, 13(4), 571-574.

Yaksh T and Wallace M.  Opioids, Analgesia, and Pain Management. In: Brunton LL, Hilal-Dandan R, and Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, 13e, 2018 [online].  USA: McGraw-Hill Education. Retrieved from http://accessmedicine.mhmedical.com